Product Safety: Wholesale businesses must comply with product safety regulations to ensure the products they sell are safe for consumers. This includes regulations related to labeling, packaging, and testing.

Environmental Regulations: Wholesale businesses must comply with environmental regulations related to the disposal of hazardous materials and waste.

Employment Regulations: Wholesale businesses must comply with employment regulations related to minimum wage, overtime, discrimination, and other labor laws.

Import and Export Regulations: Wholesale businesses involved in importing and exporting goods must comply with regulations related to customs, tariffs, and international trade agreements.

Tax Regulations: Wholesale businesses must comply with tax regulations related to sales tax, income tax, and other taxes.

Licensing and Permits: Wholesale businesses may need to obtain licenses and permits to operate legally in their state or region.